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Pharmacology Basics Textbook

A free, self-paced textbook in 8 chapters. Read a chapter, then drill it with the 100 companion flashcards using spaced repetition.

8 chapters · 100 cards · Updated

Chapters

  1. 1Foundations of Pharmacology

    Pharmacology is the study of drugs and their effects on living organisms. It is traditionally divided into two complementary branches. Pharmacokinetics describes what the body does...

  2. 2Pharmacokinetics: Absorption, Distribution, Metabolism, and Excretion

    Absorption is the movement of a drug from its site of administration into the bloodstream. The rate and extent of absorption depend on the route of administration, drug solubility,...

  3. 3Pharmacokinetics: Dosing Principles and Therapeutic Drug Monitoring

    The half-life of a drug, denoted t½, is the time required for the plasma concentration of the drug to decrease by 50 percent, and it is one of the most clinically important pharmac...

  4. 4Pharmacodynamics: Drug Action, Receptors, and the Therapeutic Index

    Pharmacodynamics describes how a drug produces its effects at the molecular, cellular, and whole-organism level. The dose-response curve plots the drug dose on the x-axis against t...

  5. 5Drug Interactions, Adverse Effects, and Patient Safety

    A drug interaction occurs when one drug alters the activity of another. Pharmacokinetic interactions arise when absorption, distribution, metabolism, or excretion is altered, for e...

  6. 6Antimicrobial and Analgesic Drugs

    Antibiotics are drugs that either kill bacteria (bactericidal) or inhibit their growth (bacteriostatic), and they target structures or processes that are specific to bacteria, such...

  7. 7Cardiovascular, Metabolic, and Central Nervous System Drugs

    Antihypertensive drugs lower blood pressure through several distinct mechanisms, and the choice of agent often depends on patient comorbidities. ACE inhibitors such as lisinopril,...

  8. 8Drug Development, Regulation, and Pharmaceutical Formulations

    Drug development follows a structured sequence from laboratory research to general clinical use. Preclinical testing involves laboratory and animal studies to evaluate basic pharma...

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